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My mother aged 85 who is bed bound had 2-3 episodes of hematuria. She was hospitalized and urine sample was collected with the help of a catheter. Her urine routine showed 75-80 pus cells but urine culture and sensitivity test showed no microbial growth. Her usg kub shows that she's having more than 500 cc urine retention. One kidney shows hydronephrosis with dilated ureter. Her abdominal scan shows that her bladder wall is trabeculated with diverticula. She was treated with antibiotics and her urologist prescribed niftas 100 mg 1 tab for 3 months, macpee 25 mg 3 tabs/day for 2 months and veltam 0.4 mg 1 tab for two months. Within 10 days she again had episodes of hematuria which lasted for 2-3 days. Her doc prescribed zifi 200 2 tabs per day for 7 days. After two days of zifi bleeding in urine stopped. Currently she's complaining of lower abdominal pain sometimes and strange discomfort. On checking her spo2 it shows fluctuation and there is increase in pulse rate. Today her pulse jumped to 128 and spo2 dropped to 76 and then normalised to 98. Her pulse rate has never come out to be high and spo2 has never fluctuated this much. Does macpee, veltam cause side effects? If so, whatever my mother is experiencing are the side effects of the meds she's on? She's completed approx 25 days of macpee and veltam and 30 days of niftas 100. Does she require a catheter for urinary retention? We are quite apprehensive in going for the catheter as she may try to pull it out leading to injury. My mother has history of hiatus hernia, oesophageal stricture, oesophageal ulcers, uti, osteoporosis and age-related dementia. She was having hypertension since past sev years but from past one month she is off the antihypertensive as her bp comes out to be normal. please advise. Thanks a lot.


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